Gene Ontology
An ontology for describing the function of genes and gene products
OntoBee
AberOWL
OLS
AmiGO
Bioregistry
The goal of the GeneOntology (GO) project is to provide a uniformway to describe the functions of gene products from organisms across all kingdoms of life and thereby enable analysis of genomic data
Publications
Products
| go.owl | GO (OWL edition) | The main ontology in OWL. This is self contained and does not have connections to other OBO ontologies [page] |
| go.obo | GO (OBO Format edition) | Equivalent to go.owl, in obo format [page] |
| go.json | GO (JSON edition) | Equivalent to go.owl, in obograph json format [page] |
| go/extensions/go-plus.owl | GO-Plus | The main ontology plus axioms connecting to select external ontologies, with subsets of those ontologies [page] |
| go/go-base.owl | GO Base Module | The main ontology plus axioms connecting to select external ontologies, excluding the external ontologies themselves [page] |
| go/extensions/go-plus.json | GO-Plus | As go-plus.owl, in obographs json format [page] |
| go/go-basic.obo | GO-Basic, Filtered, for use with legacy tools | Basic version of the GO, filtered such that the graph is guaranteed to be acyclic and annotations can be propagated up the graph. The relations included are is a, part of, regulates, negatively regulates and positively regulates. This version excludes relationships that cross the 3 GO hierarchies. [page] |
| go/go-basic.json | GO-Basic, Filtered, for use with legacy tools (JSON) | As go-basic.obo, in json format [page] |
| go/extensions/go-taxon-groupings.owl | GO Taxon Groupings | Classes added to ncbitaxon for groupings such as prokaryotes [page] |
| go/snapshot/go.owl | GO (OWL edition), daily snapshot release | Equivalent to go.owl, but released daily. Note the snapshot release is not archived. [page] |
| go/snapshot/go.obo | GO (OBO Format edition), daily snapshot release | Equivalent to go.owl, but released daily. Note the snapshot release is not archived. [page] |
Usages
- User
- http://geneontology.org
- Description
- The GO ontology is used by the GO consortium for functional annotation of genes
- Type
- annotation
- Examples
- annotations to transmembrane transport
- User
- https://www.uniprot.org
- Description
- Uniprot uses GO to show the function of proteins
- Type
- annotation
- Examples
- functional annotations of human Sonic hedgehog protein
- User
- https://reactome.org
- Description
- Reactome annotates activities, pathways, and cellular localization using GO
- Type
- annotation
- Examples
- protein tyrosine kinase activity of an EGFR complex
- User
- https://www.alliancegenome.org
- Description
- The Alliance of Genome Resources uses GO for model organism gene function annotation
- Type
- annotation
- Examples
- Functional summary of C elegans nsy-1 gene
- Gene Ontology Causal Activity Models for C elegans nsy-1 gene
- User
- https://www.rhea-db.org
- Description
- Rhea uses GO to describe individual biochemical reactions
- Type
- mapping
- Examples
- Glutamine scyllo-inositol transaminase reaction and associated GO term
- ID Space
- go
- PURL
- http://purl.obolibrary.org/obo/go.owl
- License
- CC BY 4.0
- Homepage
- http://geneontology.org/
- Contact
- Suzi Aleksander
- 0000-0001-6787-2901
- @suzialeksander
- Repository
- https://github.com/geneontology/go-ontology
- Tracker
- https://github.com/geneontology/go-ontology/issues/
- Domain
- biological systems
- Taxon
- All life
- Dependencies
- cl
- go/extensions/go-bridge-to-nifstd.owl
- ncbitaxon
- ro
- uberon
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- Stars
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- Contributors
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- Last Commit
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- OBO Dashboard
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