Row |
Level |
Rule Name |
Subject |
Property |
Value |
0 |
ERROR |
duplicate_definition |
obo:PBPKO_00374 |
IAO:0000115 |
Volume of placenta |
1 |
ERROR |
duplicate_definition |
obo:PBPKO_00380 |
IAO:0000115 |
Volume of placenta |
2 |
ERROR |
duplicate_definition |
obo:PBPKO_00176 |
IAO:0000115 |
Partition_coefficient of skin to plasma |
3 |
ERROR |
duplicate_definition |
obo:PBPKO_00516 |
IAO:0000115 |
Partition_coefficient of skin to plasma |
4 |
ERROR |
duplicate_definition |
obo:PBPKO_00055 |
IAO:0000115 |
Fraction of cardiac output in the portal vein |
5 |
ERROR |
duplicate_definition |
obo:PBPKO_00057 |
IAO:0000115 |
Fraction of cardiac output in the portal vein |
6 |
ERROR |
label_whitespace |
obo:PBPKO_00007 |
rdfs:label |
Body_Mass_Index |
7 |
ERROR |
label_whitespace |
obo:PBPKO_00304 |
rdfs:label |
Vmax_baso_in_vitro |
8 |
WARN |
annotation_whitespace |
obo:PBPKO_00008 |
IAO:0000115 |
Mass or quantity of heaviness of an individual. |
9 |
WARN |
annotation_whitespace |
obo:PBPKO_00060 |
IAO:0000115 |
Fractions of total blood flow |
10 |
WARN |
annotation_whitespace |
obo:PBPKO_00066 |
IAO:0000115 |
Organ volume in pbpk modeling refers to the volume of a specific organ or tissue in the body. |
11 |
WARN |
annotation_whitespace |
obo:PBPKO_00115 |
IAO:0000115 |
Volume of the gallbaldder |
12 |
WARN |
annotation_whitespace |
obo:PBPKO_00130 |
IAO:0000115 |
Ratio of a dissolved xenoboitic substance in a two-phase system. |
13 |
WARN |
annotation_whitespace |
obo:PBPKO_00137 |
IAO:0000115 |
A molecular entity that can undergo oxidation by the loss of hydrogen atom(s). |
14 |
WARN |
annotation_whitespace |
obo:PBPKO_00186 |
skos:exactMatch |
http://purl.bioontology.org/ontology/SNOMEDCT/17003006 |
15 |
WARN |
annotation_whitespace |
obo:PBPKO_00210 |
IAO:0000115 |
First pass metabolism, also known as the first pass effect or presystemic metabolism, is a phenomenon in which a drug/chemical undergoes metabolism at a specific location in the body, resulting in a reduced concentration of the active drug/chemical before it reaches its site of action or systemic circulation. |
16 |
WARN |
annotation_whitespace |
obo:PBPKO_00216 |
IAO:0000115 |
Kd in pbpk modeling refers to the dissociation constant of a drug/chemical-receptor complex, which is a measure of the affinity of the drug/chemical for its target receptor. it affects the distribution and elimination of the drug/chemical in the body. the dissociation constant (kd) is defined as the ratio of the rate constants for the forward and reverse reactions of the drug/chemical-receptor complex. |
17 |
WARN |
annotation_whitespace |
obo:PBPKO_00229 |
IAO:0000115 |
Volume of fluid cleared of xenoboitic from body per unit time. |
18 |
WARN |
annotation_whitespace |
obo:PBPKO_00230 |
IAO:0000115 |
Fecal cleared volume of xenoboitic from body per unit time. |
19 |
WARN |
annotation_whitespace |
obo:PBPKO_00231 |
IAO:0000115 |
Sweat cleared volume of xenoboitic from body per unit time. |
20 |
WARN |
annotation_whitespace |
obo:PBPKO_00232 |
IAO:0000115 |
Urine cleared volume of xenoboitic from body per unit time. |
21 |
WARN |
annotation_whitespace |
obo:PBPKO_00233 |
IAO:0000115 |
Bile cleared volume of xenoboitic from body per unit time. |
22 |
WARN |
annotation_whitespace |
obo:PBPKO_00234 |
IAO:0000115 |
Liver cleared volume of xenoboitic from body per unit time. |
23 |
WARN |
annotation_whitespace |
obo:PBPKO_00263 |
IAO:0000115 |
Bioavailability is defined as the rate and extent to which the active ingredient or active moiety is absorbed from a xenoboitic product and becomes available at the site of action (us-fda, cder, 2014a). |
24 |
WARN |
annotation_whitespace |
obo:PBPKO_00319 |
IAO:0000115 |
A one-compartment model assumes that all the tissues in the body are contained in a single compartment called the central compartment. |
25 |
WARN |
annotation_whitespace |
obo:PBPKO_00345 |
IAO:0000115 |
Inter-individual differences in anatomical and physiological characteristics |
26 |
WARN |
annotation_whitespace |
obo:PBPKO_00387 |
IAO:0000115 |
Measure of the age of a pregcy, indicating how far along the pregcy is. typically measured in weeks |
27 |
WARN |
annotation_whitespace |
obo:PBPKO_00388 |
IAO:0000115 |
Measure of the week of a pregcy, indicating how far along the pregcy is. |
28 |
WARN |
annotation_whitespace |
obo:PBPKO_00390 |
IAO:0000115 |
Rate at which drug/chemical transfer from materal circulation to amniotic fluid |
29 |
WARN |
annotation_whitespace |
obo:PBPKO_00441 |
IAO:0000115 |
Physiological barrier that separates the blood and milk compartments in lactating species. |
30 |
WARN |
annotation_whitespace |
obo:PBPKO_00474 |
IAO:0000115 |
It is one long tube continuing from small intestine and includes colon, rectum and anus |
31 |
WARN |
annotation_whitespace |
obo:PBPKO_00494 |
IAO:0000115 |
It is lengthy, upper part of large intestine |
32 |
WARN |
annotation_whitespace |
obo:PBPKO_00529 |
IAO:0000115 |
Qfiltrate is a parameter used in pbpk modeling to describe the blood flow rate to the filtrate which is used to calculate the rate of drug/chemical delivery to the filtrate. |
33 |
WARN |
annotation_whitespace |
obo:PBPKO_00531 |
IAO:0000115 |
Qgut is a parameter used in pbpk modeling to describe the blood flow rate to the gut which is used to calculate the rate of drug/chemical delivery to the gut. |
34 |
WARN |
annotation_whitespace |
obo:PBPKO_00532 |
IAO:0000115 |
Qmam is a parameter used in pbpk modeling to describe the blood flow rate to the mammary gland which is used to calculate the rate of drug/chemical delivery to the mammary gland. |
35 |
WARN |
annotation_whitespace |
obo:PBPKO_00550 |
IAO:0000115 |
Amount of substance in the adipose tissue |
36 |
WARN |
missing_definition |
obo:PBPKO_00135 |
IAO:0000115 |
|
37 |
WARN |
missing_definition |
obo:PBPKO_00312 |
IAO:0000115 |
|
38 |
WARN |
missing_definition |
obo:PBPKO_00447 |
IAO:0000115 |
|
39 |
WARN |
missing_definition |
obo:PBPKO_00459 |
IAO:0000115 |
|
40 |
WARN |
missing_definition |
obo:PBPKO_00485 |
IAO:0000115 |
|
41 |
WARN |
missing_definition |
obo:PBPKO_00500 |
IAO:0000115 |
|
42 |
WARN |
missing_definition |
obo:PBPKO_00505 |
IAO:0000115 |
|
43 |
WARN |
missing_definition |
obo:PBPKO_00512 |
IAO:0000115 |
|
44 |
WARN |
missing_definition |
obo:PBPKO_00520 |
IAO:0000115 |
|
45 |
WARN |
missing_definition |
obo:PBPKO_00523 |
IAO:0000115 |
|
46 |
WARN |
missing_definition |
obo:PBPKO_00526 |
IAO:0000115 |
|
47 |
WARN |
missing_definition |
obo:PBPKO_00527 |
IAO:0000115 |
|
48 |
WARN |
missing_definition |
obo:PBPKO_00528 |
IAO:0000115 |
|
49 |
WARN |
missing_definition |
obo:PBPKO_00530 |
IAO:0000115 |
|
50 |
WARN |
missing_definition |
obo:PBPKO_00533 |
IAO:0000115 |
|
51 |
WARN |
missing_definition |
obo:PBPKO_00534 |
IAO:0000115 |
|
52 |
WARN |
missing_definition |
obo:PBPKO_00535 |
IAO:0000115 |
|
53 |
WARN |
missing_definition |
obo:PBPKO_00536 |
IAO:0000115 |
|
54 |
WARN |
missing_definition |
obo:PBPKO_00537 |
IAO:0000115 |
|
55 |
WARN |
missing_definition |
obo:PBPKO_00545 |
IAO:0000115 |
|
56 |
INFO |
lowercase_definition |
obo:PBPKO_00137 |
IAO:0000115 |
A molecular entity that can undergo oxidation by the loss of hydrogen atom(s). |
57 |
INFO |
lowercase_definition |
obo:PBPKO_00263 |
IAO:0000115 |
Bioavailability is defined as the rate and extent to which the active ingredient or active moiety is absorbed from a xenoboitic product and becomes available at the site of action (us-fda, cder, 2014a). |
58 |
INFO |
lowercase_definition |
obo:PBPKO_00387 |
IAO:0000115 |
Measure of the age of a pregcy, indicating how far along the pregcy is. typically measured in weeks |
59 |
INFO |
lowercase_definition |
obo:PBPKO_00388 |
IAO:0000115 |
Measure of the week of a pregcy, indicating how far along the pregcy is. |
60 |
INFO |
lowercase_definition |
obo:PBPKO_00440 |
IAO:0000115 |
pH of milk |
61 |
INFO |
missing_superclass |
obo:PBPKO_00000 |
rdfs:subClassOf |
|
62 |
INFO |
missing_superclass |
obo:PBPKO_00002 |
rdfs:subClassOf |
|
63 |
INFO |
missing_superclass |
obo:PBPKO_00003 |
rdfs:subClassOf |
|
64 |
INFO |
missing_superclass |
obo:PBPKO_00217 |
rdfs:subClassOf |
|
65 |
INFO |
missing_superclass |
obo:PBPKO_00443 |
rdfs:subClassOf |
|
66 |
INFO |
missing_superclass |
obo:PBPKO_00444 |
rdfs:subClassOf |
|
67 |
INFO |
missing_superclass |
obo:PBPKO_00446 |
rdfs:subClassOf |
|